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Society, Religion and Technology Project

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Church of Scotland

Looking at the ethics of technology for a New Millennium


Director : Dr Donald Bruce



1997 General Assembly Report - Cloning Animals and Humans

A Supplementary Report to the 1997 General Assembly
from the Society, Religion and Technology Project, Board of National Mission

Accepted by the General Assembly on 22 May 1997

Contents


Motions on Cloning Passed by the General Assembly on 22 May 1997

The General Assembly of the Church of Scotland :

1. Commend the principle of the production of proteins of therapeutic value in the milk of genetically modified sheep and other farm animals, but oppose, and urge Her Majesty's Government to take necessary steps to prevent, the application of animal cloning as a routine procedure in meat and milk production, as an unacceptable commodification of animals.

2. Reaffirm their belief in the basic dignity and uniqueness of each human being under God. Express the strongest possible opposition to the cloning of human beings and urge Her Majesty's Government to press for a comprehensive international treaty to ban it worldwide.




Introduction

In February 1997, Dolly the cloned sheep became a global news sensation. Scientists at the Roslin Institute and PPL Therapeutics outside Edinburgh had rewritten the laws of biology in producing a live sheep by cloning from cells of the udder of an adult ewe by nuclear transfer.

The Director of the Church of Scotland's Society, Religion and Technology Project quickly became a focus for ethical comment, with numerous TV, radio, newspaper and magazine interviews and articles, including BBC's Newsnight and Heart of the Matter programmes, and German and Dutch national television. These opportunities arose because the SRT Project was already involved in assessing the issue, having for the last three years had an expert working group on the ethical issues of genetic engineering, one of whose members is the Roslin scientist who "produced" Dolly, Dr Ian Wilmut. As a result, SRT was in a unique position to offer informed and balanced comment to the world's media, and to influence the course of a debate in which sensation and ill-judged speculation were rife.

A very significant development was the fact that quite a lot of media picked up SRT's involvement from the Internet. This was because Dr Bruce had an written article on the ethics of cloning at the time of the first Roslin cloning discovery a year before, and had included this in SRT's own site on the World Wide Web. When the news broke, press agencies like CNN News searched for "cloning" on the Internet and found SRT's article as one of very few in existence. They put in a link to SRT from the own site, and all the world has since been following the trail - a month later, the SRT article was still receiving 400 Internet "visits" every day. This speaks volumes for the importance of SRT's work at the cutting edge of some of the most important issues which science is raising for our times. SRT identified four main issues - the basic genetic engineering work at Roslin, whether we should already clone animals, whether we might one day clone humans, and how such research should be controlled and kept accountable to the public.
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Cloning Animals

Much of the media attention focused on speculation about cloning humans, but missed the more immediate impact on animals, and the ethical questions on how far we should apply technology to them. The cloning arose from Roslin's search for more effective ways to do the existing work at PPL Therapeutics of genetically engineering sheep to produce therapeutic proteins in sheep's and cow's milk. The first product for emphysema and cystic fibrosis sufferers is undergoing clinical trials, and a range of other medical applications is in prospect. The SRT Project working group had already found this work generally ethically acceptable. There were clear human benefits, with few animal welfare or other concerns once past the experimental stage.

The new method should enable Roslin to do a more precise genetic modification using less experimental animals, but the side effect is that the resulting sheep is a clone, genetically almost identical to its founder. PPL might clone 5-10 sheep from a single genetically modified animal, but would then breed naturally thereafter to give flocks of varied sheep, but all containing the desired genetic modification. On this very limited scale, this would not seem ethically unacceptable. The possibility that farm animals might be cloned routinely for meat or milk production on a large scale is however a very different matter. In animal breeding, the need to maintain genetic diversity sets practical limits on how far cloning would make sense, but certain applications are already being considered. A breeder might wish to clone the best breeding stock to sell for feeding up for slaughter, or to found new nucleus herds. Would this be carrying our use of animals one stage too far?

For the Christian, the world around us is God's creation. Variety is one of its characteristic features, and especially at the level of higher animals and humans. The overall picture in the Bible, in commandments, stories and poetry, is of a creation whose sheer diversity is itself a cause of praise to its creator. To reduce this diversity to a strict blueprint, and produce replica animals routinely on demand, would seem to go against something basic and God-given about the nature of life. The very fact that selective breeding has its limits reflects this fact. Some would argue that cloning is thus absolutely wrong, no matter what it was being used for. SRT argues that scale and intention play a part. PPL's limited context could be acceptable since the main intention was not the clone as such but growing an animal of a known genetic composition, where natural methods would not work. What would be unacceptable would be in routine animal production, where natural methods exist, but would be side-stepped on the grounds of economics or convenience. This would represent one step too far beyond conventional selective breeding in the way we use animals as commodities. The approach that, whatever use we find for animals, we could clone them to do so more efficiently brings the mass production principles of the factory too far into the animal kingdom. Just as in the Old Testament an ox was not to be muzzled while treading out the grain, animals have certain freedoms which we should preserve. We may use animals to an extent, but we need to remind ourselves that they are firstly God's creatures, to whom we may not do everything we like.
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Human Cloning

One of the abiding SciFi nightmares has been the idea that we could one day replicate human beings asexually, just by copying material from human cells. Roslin's scientist told a Select Committee of the House of Commons that the nuclear transfer technique they have applied to produce Dolly could be in theory applied to humans, but the headlines which ran "human cloning in two years" were irresponsible exaggerations. It is by no means a foregone conclusion. Dr Wilmut and his colleagues made it quite clear that they think that to clone humans would be unethical, and most people seem to agree.

The Church of Scotland has already stated that to clone human beings would be ethically unacceptable as a matter of principle. On principle, to replicate any human technologically is a violation of the basic dignity and uniqueness of each human being made in God's image, of what God has given to that individual to no one else. It is not the same as twinning. There is a world of difference ethically between choosing to clone from a known existing individual and the unpredictable occurrence of twins of unknown nature in the womb. The nature of cloning is that of an instrumental use of both the clone and the one cloned as means to an end, for someone else's benefit. This represents unacceptable human abuse, and a potential for exploitation which should be outlawed worldwide.

In 1990 UK pioneered legislation making human cloning research illegal, but currently it would allowed the USA and several EU countries, and many other cultures with very different value systems. Some form of international treaty should be called for whereby no country would allow cloning research to be carried over from humans to animals. Realistically, there would be no way to stop a back street clinic or a dictatorship from ignoring such a treaty, but the lines need to be drawn. A second line of defence is also called for - the notion of the ethical scientist, for whom it would be against all professional principles to pursue such research. Some have argued that research should be permitted into the possibility of cloning living transplant organs from body cells. This would require more careful ethical consideration, but the danger of a "slippery slope" to full human cloning would be loom large over such an enterprise.

The Control of Such Research

This raises a last question of the control of such research. In many spheres of research there is a deficit in public accountability in the existing procedures whereby research priorities are set. There are no easy solutions to this problem, but, at the very least, it points to the need for a standing ethical commission on non-human biotechnology, whose work is open to public comment and scrutiny, in which those areas of research which are especially likely to have far reaching ethical implications are first debated in public.

Dr Donald Bruce
Director, SRT Project
4 April 1997

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SRT's CLONING AND GENETIC ENGINEERING PAGES

For a fuller discussion of these issues, the SRT Project has a set of pages on

SRT at the Church of Scotland's 1997 General Assembly


About Copyright

This page has been produced by the Society Religion and Technology Project of the Church of Scotland (SRT for short), and is copyright, © Donald M.Bruce, 1996. We're usually happy for people to reproduce all or part of our articles, but please write or email us for permission first, at our address below.

FURTHER INFORMATION

We'd be interested in any thoughts you might have on the above. Please email us a comment if you'd like to.

For more about our work on other issues, see our other SRT pages, or our SRT Publications List. If you want further information or a newsletter about the SRT Project, contact us at :

Dr.Donald M.Bruce,
SRT Project, , 121 George Street, Edinburgh, EH2 4YN, Scotland.
tel. +44 (0)131-240 2250, fax +44 (0)131-240 2239,
email srtp@srtp.org.uk

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